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A Web Platform To Integrate Bioinformatics Tools. A Case of Study
Bioinformatics has evolved considerably over the past decade due to the huge amount of data generated in the omics fields such as genomics, transcriptomics and proteomics. Biologists face new software applications and tools published every day and it is cumbersome to deal with their installation, execution and integration. To address this problem, many web applications have emerged focused in particular domains, including gene ontology and phylogenetics, that integrate widespread used bioinformatics tools. Following this approach,we present a service oriented web platform to study families of genes in plants. This is particularly important in food security where only a few specific genes may be involved in the resistance to stresses and diseases. The platform integrates in a single site several bioinformatics tools and public databases, and provides a clear workflow to resolve common problems in the analysis of genes. This allows generating phylogenetic trees, circos diagrams, interactive charts and 3D prediction of proteins. Its backend architecture makes easy to integrate new tools and functionalities by means of SOAP web services. Security is also a key point in the platform because many of the tools require whole access to operating system resources: multithreading in R, deep learning in GPGPU, etc. Flexibility is also important so, in addition to provide straightforward results, the platform allows the user fine-tuning them manually.